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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '422f3ac80901c408351a97365340c20a3f017ca409efee8577c46cd70394c069' 
  AND token = 'cCz7huqojPengETZlRgBmUMN8DuAiQ2l0EZP8cTU8tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}