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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '28be58ba5e316cb73ba299411a5769d0a57ea9ff101339383235b2f0639266e1' 
  AND token = 'VRXzH9agmSIhhge9+/2s/b70L3XeIdF/yFspSzYL9Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}