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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c757f21fd78b8a67a0343671223fa1c8836403d92aa9fe0803bd1b7061cd1187' 
  AND token = 'tJo3cpXA345EyTNnYZE0hW6wTUwB0aGSrbZew2Z41Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}