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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '721b0cc8f2165bb9c9131b49d15c78144147452f97ba0ff7090dd6b0811360b9' 
  AND token = 'EusHDEe8OjXbymuvTh56hEgWYTcA3ADsOxtElPGCMTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}