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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a5903bfef41c6535859f8875ee7984ccc6e773d41d18f0afdb762fdfa3b8789' 
  AND token = '6SBrHRQMRQ2fVKVg2JDdJdbSdzFHOxf8DJ0kp/Ya7yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}