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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49ea004d7b6a20e7a4296eef8c7cc6fba901de80214990899a293718f641f254' 
  AND token = 'jwF85v0tmXCmobomIgsg8L0d0x2ET55hPxPIyWufAao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}