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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '85acf720c6cf46df4f610fda3f39a6a4aa927bc12a6aabb475a2984ce6621543' 
  AND token = 'gZRBK6geSkou7B1HPXoi1+SSmA2Ay9pNVLbYBiea7QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}