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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45692e66ea32ca089a97de68cb15b1157696a8b551af5b41c7e2ce8b534967ac' 
  AND token = 'EW1G29kIHZDYd2UQAL6OXnHSqJV6/CGd6v4MeUlfkGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}