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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '39511412be8ee7a934fba9667740d589587bc00a30400157d4645e0d01c59b9b' 
  AND token = 'PsgwWpFjLX6hYdjcZiyreSnytA9hPlNNWLzsouM5x/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}