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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b885992e6cd8b6a946dfc4983ceb588e9b9066633ee6da321e402836d25f4857' 
  AND token = '3dY/MotpVNDruCc7A5ZDvS5SU/cUtV+9gATinjSvxg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}