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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5ead4914ee3c2d9a763d48f5ed32dd2d3c3bd4bc2970e41e46d104ac3c286621' 
  AND token = 'ujaMsgx1mPh+jF22d7VgksVrozt7JhgbUhksP6/XxM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}