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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e75d29d98fb50f12aabcccd874260343a9099ed7683a3661ff2c1d56dc1d1530' 
  AND token = 'VGxdZ9CLaJAhD0DOdTCfl+ctjC6NQmegg9mMbuOFmh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}