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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65fd47e1ea84f76f6c701644fe0e0e3e70a44eac1c9537465f05b94c0a63e530' 
  AND token = 'hMOf284dlM8EMBpcA5MKMfpYpx1afSA8w+aggTm2zS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}