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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3fc5b5cc4c7dd1ec08ee01d224a9254b12386042307c4683c4ee2e817165574d' 
  AND token = '/XlMQFPrjGsgif3HXbAhU4hkKayC5SK8QUov/ayRulQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}