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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2741bb8723534f5489c6f0e1c4c8fba70e600a8aff14e3868c4138f69fdce774' 
  AND token = 'u/DX+KZlILh1ZbchXN87pioxdp9z/Y0R1ETkMlyadtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}