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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5522e3d78ac5ca2e1737b0c8a0b903ee7a42363f8ade297f95e64ee59e19423a' 
  AND token = '/fBMSSAhkT5X8Bg3Gbz8MT46y5tc7NLBlTqdl9tvJJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}