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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22aec854577bb7db7e433dcf30b8f15e4541ade230f1bca539230a468b0eedae' 
  AND token = '7Rlr+r/FhpI/8sdPB0/wleoYm3MUfxWpQMicws9DOBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}