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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ec82a3d2e266b93a6c2186ba26a7578188cb65c0172799afb5e308b0f7fff84' 
  AND token = 'SPIDmvAw3/7E1JwHWUZzoRH91Xk4NVlJdExC4101Ma8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}