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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2a763313ea44f01aa6d54f39c4fbeed30249843c4c26aa842b8f704f8e17b08c' 
  AND token = 'QdzYS24D2P9YYvkX/5+005mAAoPPeJcFO3ud/rz53XE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}