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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '091c83a29f58b1ad0e75e88b99cc7be6be5218ee02eb2b60964342430658bcb1' 
  AND token = 'p+1Oe5TOLbXARTyZfj5tBB4QCA70/Y023E9u/m2S/5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}