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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c6621f4641ab25d641c90af4be24ecd36df284f64124dd29b76ee40e259ac95c' 
  AND token = 'j3CcaV1XQs4v3u1cG+dhI/qe1UnK6BbxrnB5LFeHOQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}