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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '184d7305f31780b8c148f1f3c78d5679f1e3211f65f34c5d529fdb978387b824' 
  AND token = '1HFENqnx7YB23W03IQwG0r8nH6yUmW1PVWtm0yL5yQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}