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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '14fe54e2effcc85011fa62e989d39bf78e01bf5ecd6be65e4751d068034dbbc2' 
  AND token = 'xXsJEI5R9q2kxWbVmdb3fRURsiNEZz11yF7ADNJ19dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}