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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7ec7ba81d5b13df2755ec2b07dfe11751990f49196b328154b0cf1e562a7408f' 
  AND token = '5gVIBdEBEvaiJN6X3KP47HNCTkFU7boEuBelHTYtiQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}