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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0c8fcef88490fc7e3e8ff3321d1c485dad33349e3cc4f3940bd34804806535c7' 
  AND token = '2XOyEcWO8CpvNh2uD7IV7WnUWAAhNM3LiTIMAKqWNZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}