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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3bf222cdc87f6f478825d475b4147f6481eb9fc13d0dce8da8c548acd32a7297' 
  AND token = 'blXNLC9AuaCY9bi9G6BufkGElHiaO9Ru/c6koRdo+LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}