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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a6d57c47550c3bcbdd9b251bd40709fa4ac84009320ba3f4776b904aacd7d400' 
  AND token = '69l4sWam959melnEoC0XoNq/67ePfGGPtY31cgzdBUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}