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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '501659e0a5b05eccee83c07e29fdd37f1c9bf73f73b9f6125626abb1427bc6cb' 
  AND token = 'Ru25UZC4ZiV/cgj52s7PAA2TaaAznYl5aVAAWzrJ6zQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}