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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cedfa64ea5d0d554e49eb99962d4580480cda39ebd05ce18267e8014f1fc180f' 
  AND token = 'Wlp5d0B9pu5CeQyDmfS/YNDrTaCFGFs9AItfVObllGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}