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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2e0222fe1ea60e457616f731f8428aed1bdbd76cb96007da9ab1d631d70d4ab' 
  AND token = 'Ve1pPRHl4LsdZD1wHf5cUOqulDFnBjqMtk+wGk92TnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}