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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '05c4237208cf2141a85fe892629c4f87f4bd6e18ad478cff8e10e8274e53f8cc' 
  AND token = '8A5XsqAdpXMvsk6a5mn9k2XsGMWcs7L8t1lC1/WD1KM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}