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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '79b3a222e47b67b9fcd408e722a3c02c5c1141dbf52e3fe754d246bf00eede49' 
  AND token = 'FJn8kyY3bDJDMEMu8523hVOFTsxc/07nJOXP6102g7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}