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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '14c83e7b4d17bd7da68d16f0a1cd10025c452fd6e0c8395022098a7d392e41f0' 
  AND token = 'CsNAe0HjqR7zw4XEFFtnImfFb5hBl9cN0QeUPJuR9Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}