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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ff85249ab62fecc936f7b757bb0055c1a152e04d3e0756ad27cb17c7cf307f64' 
  AND token = 'vYxAoAPSvGf33SwkRY0cMYLTxk4BdjnStJ4qdbN9rLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}