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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b0385d10352a2d22c818c55de577f55f61eb27caa94d4170e36a0266abcb6dc' 
  AND token = 'nAUr8AKTcEcFSMKulfrrnZRGZx/kam/9cU6pHuDlQ6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}