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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49148b936b08d65d30704cb2356090b1bdabb182876f2636e95a5b88ad4fab36' 
  AND token = 'A+zdx31eC/O9bwHi6CaE1c470LMlOvUZwcEMxCyCw1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}