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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5e55093dd16b715a3132bda3f0220586f3993bac1a996d61f25c69d19f3aa89' 
  AND token = 'A6yWFtyRteJX8y2YA/rI8kWKYbCzMm8GsuWczamIDGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}