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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '82258f8c671c86b7df70b797eb8f18cad04ca976b14606b4f01d4aa02d78798d' 
  AND token = '4QW2ZpHnmvEBhCB/9D2jbOCitWhCXtNpZvZlspy6Gjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}