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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '27932acb17826e4dea75d86e513e6add1290b441161a29d237a164c7b8a6a2f9' 
  AND token = 'C5NtO8AG5c9qF/Ao4uz/lcqY7caLihtKn+dk3J0R/o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}