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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a6111c2bd172f1231c6b022c249e754be7e10369f304aa714b97d3696c25265e' 
  AND token = 'w6jqQiOSAU2sJU9+qEJiAfianbYU98e0ycWECuzUlrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}