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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9df8a2cfae48f58a0a0585a1922909abdb8fb8730a60c670d6902e3802ec82da' 
  AND token = '18JMSphEE4aiUSW5VPsU2g+q2JQveiQmj1vbGhlemPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}