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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3ed082f31b297515f1e52f6e66919b3c011c0369a81c74c428201a5d9292b1eb' 
  AND token = '6/sVA9TlW2Oij92FPUUugFiKmUyz7p2lkYsc78zE8EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}