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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '300c12eddc2104700b64c1876944621c6b5e867267a0def3d7a555aff739816f' 
  AND token = 'JQoERKNPIRVWAnMZg2NGyEyNsrg3hqI4115Q1Yh0mgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}