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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '82f1ab5e98513abed61b2eed39087f44ca2633d430037549f68124f1e1c27421' 
  AND token = 'VL3zt3HXT0nasI9jFtuEPY3OUOFcwtOg0kO2MNxiLp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}