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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5ff2afa1aeecbc6661e0f10b2dea47af438739ad686f969a76f40a18355b5e41' 
  AND token = 'ZjK3d3Gqs5+s50y9SoaeY9EcoGnN9onE5fQ3EtMCO9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}