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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f600549a6a7b941d2df157b4acc841e8b1aec9a67640cdedbfdcd46fdc5232cf' 
  AND token = 'Y2c5DHxz+4sc7b1rgRPFIKLP98rEheu/k2aZvvrCzf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}