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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f6d21eed5de8035cbaf6227a2310f4143bbaaa6c145b444988caca813ea1b914' 
  AND token = 'Bb2LRRG49h4EYWI4NDRFkT991T+tEf5hOCg6/vimvDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}