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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22f816155e1b0139da220c346ebe316542ab77112a42222958de8f6d7e026dd4' 
  AND token = '7RWwTsZ+ICDgfC7Z03kw2OAS6vLlCtiUBUhkZ1qASdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}