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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0764739f25577b5c6263c8b759dd1ace996bb0409b7e129ad115d374d5f75306' 
  AND token = '2e/3LyMx8EHJOlxit7C1/AybYOQi5f48qvemAQfBEOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}