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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b72f009bb09ca4933c4e1bde317ada54a686bd7b8a2f1d175f560854092e1b95' 
  AND token = 'RylZ6fk+MQsPf7JwrdOWEyuEyRbei6+ZYOAGPkrrIrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}